PUEB research projects 2018-2020

Synthesis, surface and antimicrobial properties of novel sulfobetaines and the possibilities of their use in medical products

Sources of funding :
•The National Centre for Research and Development (Poland), 
• Ministry of Science and Technology (Taiwan)
Polish-Taiwanese bilateral project in frame of Poland-Taiwan cooperation

Call: 4th Polish-Taiwanese call for joint research projects

Project ID number: PL-TW IV/2/2017
Start date: 01.04.2017
Finish date: 31.03.2020
Amount of funding: 395 000 PLN (UEP) + 3 600 000 TWD (NTU)

Abstract:

 

Surfactants, thanks to the structure of the molecule consisting of hydrophilic head and hydrophobic tail, show many interesting properties. The most important characteristics are their ability to reduce surface tension as well as wetting, solubilizing, emulsifying and antimicrobial properties. Sulfobetaine surfactants are one of the groups of surfactants which may show antimicrobial effects. As a result of their specific structure, they can exhibit many desirable features at the same time and are a research material of high potential.

 

The cooperation between the teams of the Poznań University of Economics and Business and the National Taiwan University in Taipei, established in 2013, resulted in the publication of an article in the Journal of Surfactants and Detergents (DOI: 10.1007/s11743-016-1838-3). The results of the joint research have been noticed and served as basis for further cooperation, which is why the teams have been recommended for funding research from the National Centre for Research and Development. The objectives of the project include:

 

- synthesis of sulfobetaine surfactants and their spectroscopic characteristics, as well as the characteristics of surface activity;

- evaluation of antimicrobial activity, as well as the therapeutic and toxic effects of the synthesised compounds.

 

The obtained results will allow for a broad characterization of surface and antimicrobial activity of sulfobetaine obtained and will indicate the potential use of these compounds as substances with therapeutic effect.

 


Co-investigators:
dr hab. inż.  Daria Wieczorek, prof. UEP
Department of Technology and Instrumental Analysis, Institute of Quality Science

dr Dobrawa Kwaśniewska
Department of Technology and Instrumental Analysis, Institute of Quality Science


Department of Plant Pathology and Microbiology, National Taiwan University, Taipei, Taiwan